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C1 Inhibitor is a multi-specific protease inhibitor present in human plasma and serum. Among the proteins it regulates are C1s and C1r of the C1 complement complex.
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Purified human complement component C1q. Circulating C1q protein is a hexamer of three unique protein subunits (A,B, and C) with molecular weights of 29, 26 and 22 kD respectively.
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Complement protein C1r is a serine protease that combines with C1q and C1s to form C1, the first component of the classical pathway of the complement system.
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Complement protein C1s is a serine protease that combines with C1q and C1r to form C1, the first component of the classical pathway of the complement system.
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Complement protein C2, which is part of the classical pathway of the complement system, is cleaved by activated factor C1 into two fragments: C2b and C2a. C2a, a serine protease, then combines...
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The complement pathway generates a C3 convertase, a serine protease that cleaves the central complement protein C3, and generates the major cleavage fragment C3b.
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The complement pathway generates a C3 convertase, a serine protease that cleaves the central complement protein C3, and generates the major cleavage fragment C3b.
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Human serum chemically depleted of C4 protein
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Derived from proteolytic degradation of complement C4, C4a anaphylatoxin is a mediator of local inflammatory process.
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C4b is a cleavage product of complement protein C4, along with C4a. C4b is a non-enzymatic component of the C3 and C5 convertases and thus essential for the propagation of the classical complement...
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C5a, or C5 anaphylatoxin, is a mediator of local inflammatory process. It induces a variety of responses including intracellular calcium release, contraction of smooth muscle, increased vascular...
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Purified human complement component C6.
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A centrally important reaction that occurs during alternative pathway activation is the conversion of the Factor B zymogen to an active proteolytic enzyme.
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Human serum immunochemically depleted of Factor D protein. Quidel's depleted sera are specifically depleted of a single complement protein. With the exception of the depleted protein, the...
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iC3b is generated during the activation of the complement system via the classical or alternative pathway. When a convertase enzyme cleaves C3, C3a and C3b are released in parallel.
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Klotho, named after one of the Fates in Greek mythology, is a type-I transmembrane protein that is associated with many functions. A novel ß-glucuronidase, Klotho has been associated with...
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Klotho, named after one of the Fates in Greek mythology, is a type-I transmembrane protein that is associated with many functions. A novel ß-glucuronidase, Klotho has been associated with...
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A murine monoclonal antibody to an epitope in the C3d domain of C3
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A murine monoclonal antibody to human C4d containing fragments
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A murine monoclonal antibody to an epitope in the Bb fragment of Factor B
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A murine monoclonal antibody to human Factor H
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A murine monoclonal antibody to human Factor H
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A rabbit antiserum raised against human complement C3a protein. C3a, along with C3b, is a cleavage product of complement protein C3. C3a is a anaphylatoxin that binds to the C3aR receptor.
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A rabbit antiserum raised against human complement C4a protein. C4a is a protein fragment from the cleavage of complement protein C4, along with C4b.
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A goat antiserum raised against human Factor D protein. Factor D is unique to the Alternative Complement Pathway. It consists of a single peptide chain with a molecular weight of 24 kD.
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A goat antiserum raised against human complement Factor P protein.
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A rabbit antiserum raised against human complement SC5b-9 protein. SC5b-9 is the soluble version of the terminal complement complex (TCC). The TCC is a multi-protein complex consisting of...
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A rabbit antiserum raised against human complement Vitronectin protein.