Monoclonal Antibody to Human Factor H#2

For Research Use Only. Not for use in diagnostic procedures.

A murine monoclonal antibody to human Factor H

This monoclonal antibody was raised against purified human Factor H.

Quidel's Factor H monoclonal antibody has been used in a variety of experimental techniques including EIA and Western Blot. Please contact Quidel Technical Support for details on any applications.

References

Pangburn M.K. Differences between the binding sites of the complement regulatory proteins DAF, CR1 and Factor H on C3 Convertases, J Immunol 136:6, 1986.

Kraiczy P, Würrzner, R. Complement escape of human pathogenic bacteria by acquisition of complement regulators, Mol Immunol 43:31-44, 2006.

Atkinson, J.P., et al. Complement factor H and the hemolytic uremic syndrome, JEM 204:6, 1245-1248, 2007.

Sivaprasad, S. and Chong, N.V. The Complement system and age-related macular degeneration, Eye 1-6, 2006.

Jokiranta, T.S., et al.  Analysis of the recognition mechanism of the alternative pathway of complement by monoclonal anti factor H antibodies: evidence for multiple interactions between H and surface bound C3b, FEBS Ltr 393(2-3):297-302, 1996.

Junnikkala S., et al.  Exceptional resistance of Human H2 Glioblastoma Cells to Complement Mediated Killing by Expression and Utilization of Factor H and Factor H Like Protein I, J Immunol 164, 2000.

Cheng Z., et al. Complement Factor H as a Marker for Detection of Bladder Cancer, Clin Chem 51:5, 2005.