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Monoclonal Antibody to Human C3d

For Research Use Only. Not for use in diagnostic procedures.

A murine monoclonal antibody to an epitope in the C3d domain of C3

The specificity of the monoclonal antibodies was established via a series of immunological techniques, including ELISA, hemagglutination, and RIA. The antibody was shown by ELISA to bind C3 antigens using highly pure, immobilized C3. The antibody agglutinates EiC3b, EC3b, and EC3d cells in an indirect hemagglutination assay. Finally, the antibody bound to radio-labeled purified iC3b, C3b, and C3d, but not similarly labeled C3 or C3c.

Quidel's C3 (C3d) monoclonal antibody has been used in a variety of experimental techniques including EIA and Immunohistochemistry. Please contact Quidel Technical Support for details on these or other applications.

References

Tamerius, J.D., Pangburn, M.K., et al. Detection of a neoAntigen on human iC3b and C3d by monoclonal Antibody, J. Immunol. 135:2015, 1985.

Tamerius, J.D., Pangburn, M.K., et al. Selective inhibition of functional sites of cell bound C3b by hybridoma derived antibodies, J. Immunol 128:512, 1982.

Rogers, J., Cooper, N., et al. Complement Activation by ß-amyloid in Alzheimer disease. PNAS 89:10016-10020, 1992.

Features & Benefits

FeatureBenefit

Product Specifications

Product Spec NameProduct Spec Data
Isotype

lgG1k

Protein concentration

> 1.0 mg/mL

Volume/vial

100 µL

Storage

2°C to 8°C

Ordering Information

Catalog NumberKit Size / Case Size
A250
100 µL

Product Documentation

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