C4b Protein

For Research Use Only. Not for use in diagnostic procedures.

C4b is a cleavage product of complement protein C4, along with C4a. C4b is a non-enzymatic component of the C3 and C5 convertases and thus essential for the propagation of the classical complement pathway. It also binds to immunoglobulins and immune complexes, enhances the solubilization of immune aggregates, and the clearance of IC through CR1 on erythrocytes.

All Quidel complement components are tested for functional activity in a standard lytic or applicable functional assay and for biochemical purity by SDS-polyacrylamide gel electrophoresis. Please refer to the Certificate of Analysis for lot specific information on functional titer.

Quidel's purified human complement components are useful in a wide variety of immunochemical and research applications. For assistance with a specific protocol, please contact Quidel Technical Support.