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The Quidel Triage PLGF Test is used in conjunction with other clinical information as an aid in the diagnosis of preterm pre-eclampsia and as an aid in the prognosis of delivery, in women presenting with signs & symptoms of pre-eclampsia after 20 weeks and prior to 35 weeks of gestation.


Pre-eclampsia is a complex clinical syndrome that can progress rapidly and unpredictably. Frequent and costly clinical assessments are often required to differentiate those women who will deliver preterm from the majority of women who will deliver at term. Current methods for assessing risk include measurement of maternal blood pressure, identifying the presence of protein in the urine, and laboratory blood testing to detect maternal organ damage. These methods are poor in determining a woman’s level of risk for spontaneous or iatrogenic delivery. Limitations with today’s tests make it difficult to discriminate women with severe disease from those with mild or no disease, leading to over-management and unnecessary costs.

Placental Growth Factor (PLGF) is a highly specific marker of failed placentation and its complications, including pre-eclampsia. In women with hypertension, PLGF is predictive of the development of preterm pre-eclampsia, with the lowest levels found in women who progress to an adverse pregnancy outcome.

For further information please visit Quidel’s dedicated PLGF resource page plgf.com


Levine R, et al. (2004) Circulating Angiogenic Factors and the Risk of Preeclampsia. New England Journal of Medicine; 350:7.

Chappell LC et al. (2012) Plasma placental growth factor (PLGF) measurement in women presenting with suspected pre-eclampsia: the Pelican study.

Pregnancy Hypertension: An Intl Journal of Women’s Cardiovascular Health 2; 175-239.

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Features & Benefits


Highly specific for PLGF isoform-1

Measurable range of 12 pg/mL - 3,000 pg/mL

Utilizes the Quidel Triage MeterPro

Quickly, economically and effectively identifies placental dysfunction as a root cause of preterm pre-eclampsia

Aids in diagnosing preterm pre-eclampsia

Aids in risk stratifying women in their first presentation with suspected preterm pre-eclampsia for iatrogenic delivery within 14 days

Helps appropriately adjust clinical surveillance and, where indicated, plan for preterm delivery

Product Specifications

Product Spec NameProduct Spec Data
Sample type

EDTA anticoagulated plasma specimens

Time to results

Yields results in about 15 minutes

Ordering Information

Catalog NumberDescription
Quidel Triage PLGF Test
Quidel Triage PLGF Control 1
Quidel Triage PLGF Control 2