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Thyretain utilizes a genetically engineered cell line that expresses a human Thyroid Stimulating Hormone receptor (hTSHr) and a Luciferase reporter gene. The luciferase enzyme is measured through a luciferase-luciferin chemiluminescent reaction when the cell line is incubated with patient serum containing Thyroid Stimulating Immunoglobulins (TSI).

 

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