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Intended Use For Research Use Only. Not for use in diagnostic procedures.
Catalog Number A207
Price $234.00 (U.S. List Price)
Size 100 µL
Application EIA, FACS, IHC, RIA, WB
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Description

For Research Use Only. Not for use in diagnostic procedures.

A murine monoclonal antibody to an epitope in the C3d domain of C3.

This monoclonal antibody was raised against purified human C. It is specific for an antigen expressed on the C3d domain of C3 and therefore reactive to C3 and all C3d-containing fragments of C3.

Quidel's C3 (C3d) monoclonal antibody has been used in a variety of experimental techniques including EIA, Western Blot, and Immunohistochemistry. Please contact Quidel Technical Support for details on these or other applications.

References

10 References

Shields KJ, Mollnes TE, Eidet JR, Mikkelsen K, Almdahl SM, et al. (2017) Plasma complement and vascular complement deposition in patients with coronary artery disease with and without inflammatory rheumatic diseases. PLOS ONE 12(3): e0174577.

Perez LG, Martinez DR, deCamp AC, Pinter A, Berman PW, et al. (2017) V1V2-specific complement activating serum IgG as a correlate of reduced HIV-1 infection risk in RV144. PLOS ONE 12(7): e0180720.

Seddon JM, Yu Y, Miller EC, et al. Rare variants in CFI, C3 and C9 are associated with high risk of advanced age-related macular degeneration. Nature genetics. 2013;45(11):1366-1370.

Martini PG, Cook LC, Alderucci S, et al. Recombinant human complement component C2 produced in a human cell line restores the classical complement pathway activity in-vitro: an alternative treatment for C2 deficiency diseases. BMC Immunology. 2010;11:43.

Carlsson F, Berggård K, Stålhammar-Carlemalm M, Lindahl G. Evasion of Phagocytosis through Cooperation between Two Ligand-binding Regions in Streptococcus pyogenes M Protein. The Journal of Experimental Medicine. 2003;198(7):1057-1068.

Stoltzner, S., Lemere, C. et al. Temporal accrual of complement proteins in Amyloid plaques in patients with Down syndrome with Alzheimer's Disease, Am J Path 156:489-499, 2000.

Gemmell, C. A flow cytometric immunoassay to quantify adsorption of complement activation products on artificial surfaces, J Biomed Mater Res 37, 474-480, 1997.

Rogers, J., Cooper, N., et al. Complement Activation by ß-amyloid in Alzheimer disease. PNAS 89:10016-10020, 1992.

Tamerius, J.D., Pangburn, M.K., et al. Selective inhibition of functional sites of cell bound C3b by hybridoma derived antibodies, J. Immunol 128:512, 1982.

Tamerius, J.D., Pangburn, M.K., et al. Detection of a neoAntigen on human iC3b and C3d by monoclonal Antibody, J. Immunol. 135:2015, 1985.

Features & Benefits

FeatureBenefit

Product Specifications

Product Spec NameProduct Spec Data
Isotype

IgG1k

Protein concentration

> 1.0 mg/mL

Volume/vial

100 µL

Storage

2°C to 8°C

Ordering Information

Catalog NumberKit Size / Case Size
A207
100 µL

Product Documentation