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Factor D

For Research Use Only. Not for use in diagnostic procedures.

Purified human complement Factor D. Factor D is unique to the Alternative Complement Pathway. It consists of a single peptide chain with a molecular weight of 24 kD. Factor D is a specific serine protease which cleaves Factor B complexed with C3b (or hydrolyzed C3) in a single position to yield Bb and Ba.

All Quidel complement components are tested for functional activity in a standard lytic or applicable functional assay and for biochemical purity by SDS- polyacrylamide gel electrophoresis. Please refer to the Certificate of Analysis for lot specific information on functional titer.

Quidel's purified human complement components are useful in a wide variety of immunochemical and research applications. For assistance with a specific protocol, please contact Quidel Technical Support.

References

Marks, R. Hindmarsh, E. Complement activation occurs on subendothelial extracelluslar matrix in vitro and is initiated by retraction or removal of overlying endothelial cells, J Immunol 160:6128-6136, 1998.

Barbashov, S., Wang C., Nicholson-Weller, A. Serum amyloid P component forms a stable complex with human C5b-6, J. Immunol. 158:3830-3835, 1997.

 

Features & Benefits

FeatureBenefit

Product Specifications

Product Spec NameProduct Spec Data
Concentration

0.1 mg/mL

Volume/vial

250 µL/vial

Storage

At or below –70°C

Purity

> 90%

Buffer

PBS

Ordering Information

Catalog NumberKit Size / Case Size
A409
250 µL/vial

Product Documentation

PDF icon  SDS