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Solana Respiratory Viral Panel

The Solana Respiratory Viral Panel (RVP) combines two Solana respiratory assays, Solana Influenza A+B and Solana RSV + hMPV, to create a focused respiratory viral panel to detect and differentiate all four respiratory viruses (influenza A, influenza B, respiratory syncytial virus and human metapneumovirus) from a single patient sample. Test up to 6 patients at a time in just 45 minutes using Solana’s high-volume throughput.

Solana Influenza A+B and Solana RSV + hMPV each amplifies and detects viral RNA present in transport media containing nasopharyngeal or nasal swab specimens obtained from symptomatic patients.

The process buffer is universal between both kits, which allows testing for all four conditions using a single patient sample. Testing is done using two major steps: (1) specimen preparation, and (2) amplification and detection of target sequences specific to RSV, hMPV, influenza A and/or influenza B using isothermal Reverse Transcriptase – Helicase-Dependent Amplification (RT-HDA) in the presence of target-specific fluorescence probes which is performed in the Solana instrument.

Results are displayed on the touchscreen, can be saved to the instrument, printed, and are capable of being sent to the LIS and exported through one of Solana’s five USB ports. Manage de-identified data, in near real time for improved operational efficiencies, using the Power of Virena®, which is integrated directly into Solana.

Features & Benefits

FeatureBenefit
Universal buffer solution

Test for all four viruses using a single patient sample

Small, easy-to-use instrument

Great for smaller labs. Saves space at 9.4" x 9.4" x 5.9". Eliminates the need for dedicated molecular space and costly capital equipment.

Power of Virena

Manage data and resources for a single site, or multiple sites from any web-enabled device. Report and monitor disease prevalence in your community.

RT-HDA technology

Rapid method of isothermal nucleic acid amplification that does not require thermal cycler

Lyophilized Master Mix reagent

Easy-to-use format, just add processed sample to rehydrate

CLIA moderately complex

Requires minimal training

Refrigerated storage

No freezer needed, 2˚C to 8˚C storage

Long shelf life

Currently 12 months from date of manufacture

Room temperature set up

No ice or cooling block required

Product Specifications

Product Spec NameProduct Spec Data
Sample type
Nasal swabs and nasopharyngeal swabs in transport media* obtained from patients symptomatic of respiratory infection

*BD/Copan VTM, Remel M4, Remel M4RT, Remel M5, Remel M6, or Copen eSwab

Note: Influenza A+B specimens collected in Copan eSwab transport media are stable at 2° C to 8°C for up to 48 hours

Time to results

Approximately 45 minutes

Reagent storage conditions

Lysis and Reaction Tubes; 2˚C to 8˚C

Controls storage conditions

2°C to 8°C

Sample preparation storage conditions

Specimens should be collected, transported, stored, and processed according to CLSI M41-A and stored at 2°C to 8°C until tested. Specimens collected in BD UTM, Remel M4, M4RT, M5, and M6 (3 mL), and Copan eSwab are stable at 2°C to 8°C for up to 9 days

PPA (PCR)
RSV: 95.5% (95% CI 91.0% to 97.8%)
hMPV: 95.6% (95% CI 89.1% to 98.3%)
Influenza A: 97.2% (95% CI 95.0% to 98.4%)
Influenza B: 100.0% (95% CI 95.4% to 100%)
NPA (PCR)
RSV: 99.9% (95% CI 91.0% to 97.8%)
hMPV: 99.8% (95% CI 99.6% to 99.9%)
Influenza A: 96.7% (95% CI 95.4% to 97.7%)
Influenza B: 98.9% (95% CI 98.2% to 99.4%)
LOD (RSV)
RSV A, A2 (VR-1540): 7.9x103 TCID50/mL
RSV B, Wash/18537/62 (VR-1580): 3.9x102 TCID50/mL
LOD (hMPV)
hMPV 16 Type A1, IA10-2003: 3.7x10² TCID50/mL
hMPV 20 Type A2 IA14-2003 G gene: 1.2x104 TCID50/mL
hMPV 5 Type B1, Peru3-2003: 3.8x10³ TCID50/mL
hMPV 4 Type B2, Peru1-2002: 2.3x10³ TCID50/mL
LOD (Influenza A)
A/Taiwan/42/06: 7.5x102 TCID50/mL
A/California/07/2009: 4.7x102 TCID50/mL
A/Texas/50/2012: 6.3x100 TCID50/mL
LOD (Influenza B)
B/Brisbane/60/08: 8.5x101 TCID50/mL
B/Massachusetts/2/2012: 3.3x101 TCID50/mL

Ordering Information

Catalog NumberDescriptionKit Size / Case Size
M925
Solana Respiratory Viral Panel Kit
1 Solana Influenza A+B Assay test kit (48 tests)
1 Solana HSV + hMPV Assay test kit (48 tests)
96 tests
M926
Solana Respiratory Viral Panel Control Set
1 Solana Influenza A+B Control Set
1 Solana HSV + hMPV Assay Control Set
20 mL

Product Documentation